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The ivermectin wars - people on both sides of the debate are lying.


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https://www.realclearscience.com/articles/2021/09/08/lessons_from_the_ivermectin_debacle_793483.html

 

Here is the most balanced article on ivermectin.

 

Bottom line:  Ivermectin is not just a "horse dewormer."  It is an effective human dewormer too.  But is it a covid cure/prophylactic? 

 

It showed initial promise in anecdotal, correlational and petri-dish studies - it was worth a shot.  Unfortunately, more detailed analyses have shown that the initial promise was unwarranted, many of the positive studies were terrible/fraudulent/both and so the jury is still out.  More studies are on the way, and we will know soon. 

 

On the flip-side, it is not a villain, and all those stories of 1000s of people being poisoned by ivermectin overdosing?  Not true.  

 

 

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FDA approved only for specific use in human beings.  So far the official number is 459 cases. For countries like USA where political polarization is extreme,  suggesting unproven drugs (based on anecdotal evidence) can prove to be catastrophic. They don't trust doctors who prescribe vaccine but they trust doctors who prescribe ivermectin? They have turned this into a political circus. 

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On 9/10/2021 at 12:09 AM, rkt.india said:

People are taking ivermectin for years for deworming. Now because they consumed it for Covid, it becomes toxic. In Uttarakhand, every household was distributed ivermectin by govt with instructions of how much to take for how many days.

They take it under doctor prescription and doses. Not randomly on the street. 

 

There is no known benefit for covid. 

 

Any medicine becomes toxic if taken over the counter and without restricted doses. Even crocin or aspirin

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6 hours ago, New guy said:

They take it under doctor prescription and doses. Not randomly on the street. 

 

There is no known benefit for covid. 

 

Any medicine becomes toxic if taken over the counter and without restricted doses. Even crocin or aspirin

People aren't fool enough to consume it every second hour. It was instructed to take two tabs per day for 5 days only for adults, one tab for kids.

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1 hour ago, rkt.india said:

People aren't fool enough to consume it every second hour. It was instructed to take two tabs per day for 5 days only for adults, one tab for kids.

I am not talking about the india situation at all. In US issue is, they have far better medicines available and patients and their families are fighting the doctors to take this medicine and often getting it from elsewhere and overdosing on it

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QAnon Anti-Vaxxer Whose Followers Harassed Hospital for Ivermectin Dies of COVID-19

 

https://www.vice.com/en/article/epn3dz/qanon-anti-vaxxer-whose-followers-harassed-hospital-for-ivermectin-dies-of-covid-19?utm_source=vice_facebook&utm_medium=social&fbclid=IwAR1s49dlJ91Cls1llrg8yV8EnubtyT03CWD5mJF9NQL_uiPuxLfGG0v7GNA

 

Idiots. Dying of a preventable illness.

Edited by EnterTheVoid
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I had given this drug the BOTD.  I was wrong to do so.  Maybe the jury is still out, but it ain't looking good. 

 

https://retractionwatch.com/2021/11/02/ivermectin-covid-19-study-retracted-authors-blame-file-mixup/

 

 

was found to have blocks of details of 11 patients that had been copied and pasted repeatedly – suggesting many of the trial’s apparent patients didn’t really exist.

The study’s authors told the BBC that the ‘original set of data was rigged, sabotaged or mistakenly entered in the final file’ and that they have submitted a retraction to the scientific journal which published it.

 

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Ivermectin - the Graeme Hick of CoViD-19 treatments.  Lots of hype.  Lots of debate.  Short stay. 

 

https://www.nejm.org/doi/full/10.1056/NEJMoa2115869

 

Methods

We conducted a double-blind, randomized, placebo-controlled, adaptive platform trial involving symptomatic SARS-CoV-2–positive adults recruited from 12 public health clinics in Brazil. Patients who had had symptoms of Covid-19 for up to 7 days and had at least one risk factor for disease progression were randomly assigned to receive ivermectin (400 μg per kilogram of body weight) once daily for 3 days or placebo. (The trial also involved other interventions that are not reported here.) The primary composite outcome was hospitalization due to Covid-19 within 28 days after randomization or an emergency department visit due to clinical worsening of Covid-19 (defined as the participant remaining under observation for >6 hours) within 28 days after randomization.

Results

A total of 3515 patients were randomly assigned to receive ivermectin (679 patients), placebo (679), or another intervention (2157). Overall, 100 patients (14.7%) in the ivermectin group had a primary-outcome event, as compared with 111 (16.3%) in the placebo group (relative risk, 0.90; 95% Bayesian credible interval, 0.70 to 1.16). Of the 211 primary-outcome events, 171 (81.0%) were hospital admissions. Findings were similar to the primary analysis in a modified intention-to-treat analysis that included only patients who received at least one dose of ivermectin or placebo (relative risk, 0.89; 95% Bayesian credible interval, 0.69 to 1.15) and in a per-protocol analysis that included only patients who reported 100% adherence to the assigned regimen (relative risk, 0.94; 95% Bayesian credible interval, 0.67 to 1.35). There were no significant effects of ivermectin use on secondary outcomes or adverse events.

 

/thread

 

 

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The longer the name of a drug, the more I'm convinced of its therapeutic properties. Makes me feel that the molecule is fairly complicated and there has been sufficient research to reach that complex sounding name.

 

If you packaged the same shell drug (placebo) under two labels: Zil and Visteraformamenthaline, I'm sure I'd feel a lot better after taking the latter.

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