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Posted
11 minutes ago, coffee_rules said:

you reduce your chances of hospitalization and death if vaccinated, otherwise if you get infected, you might be asymptomatic or have mild symptoms like a common cold.

asymptomatic is a made up word. im sure before they said the word, you wouldnt have known what it is. How can you be carrying a disease without any symptoms. They want people with common cold to get checked up and end up with a false positive, get hospitalized and killed in the process. quarantine and kill

Posted (edited)
30 minutes ago, coffee_rules said:

you reduce your chances of hospitalization and death if vaccinated, otherwise if you get infected, you might be asymptomatic or have mild symptoms like a common cold.

Recent real-world data from Israel and the UK has shown that transmissibility has also been drastically reduced due to the vaccine.  

https://www.nature.com/articles/d41586-021-00316-4

https://www.bbc.com/news/uk-55913913

 

Sometimes, scientists get in their own way with "maybe" "chances are," "better to be careful" "keep your mask on" "waiting for data" statements.  Although it is intuitive that vaccine reduces viral load, which will lead to decreased transmissibility, they will not tell you that until someone actually *measures* transmissibility itself.  And that involves complicated stats (ask @G_B_).  So, you'll hear caution and people interpret it like "so, what's the point of vaccine?  why should I wear mask?"  

 

Now the real-world transmissibility data are there, and they look great.   Even now, you hear "it's not peer-reviewed yet" from scientists, adding fuel to the naysayers' points.  But I'd rather have it this way.  

 

Bottom line is:  This is brand new virus, with brand new capabilities.  And we have brought it to its knees in record time.  Light, meet tunnel.  

Edited by BacktoCricaddict
Posted
4 hours ago, Mariyam said:

@BacktoCricaddict @FischerTal @Khotaand the other science/biology people here. My noob question:

 

Why do we start by inoculating the senior citizens? For the most part, they are indoors. Thereby of all sections of the population, their propensity to catch the virus is the lowest.

Shouldn't we instead inoculate the younger/ working people *first*? There is some research showing that younger people are asymptomatic carriers for a few days longer. Also if they are inoculated, they will not infect the elders at their place. By extension the elders are also safe.

 

Depends how you look at it.

Fatality rate is disproportinately higher among elder population. In UK 100x than the general population so that is why the guidelines are to vaccinate them first.

Old people when they get sick will clog all the resources and this keeps them out of hospital.

Posted

I'll tell you another thing. The hospitals especially in the west which if you go by news is overflowing with corona patients are actually empty. Many youtubers who showed this with their video cameras were shut down from youtube because of "misinformation". They tell doctors and nurses dance to beat the stress. They probably do it due to boredom. I would wager that they are actually c grade dancers posing as doctors and nurses. what a choreographic dance moves they have

 

Read the comments. nobody is believing this propaganda :laugh:

Posted
4 hours ago, Mariyam said:

@BacktoCricaddict @FischerTal @Khotaand the other science/biology people here. My noob question:

 

Why do we start by inoculating the senior citizens? For the most part, they are indoors. Thereby of all sections of the population, their propensity to catch the virus is the lowest.

Shouldn't we instead inoculate the younger/ working people *first*? There is some research showing that younger people are asymptomatic carriers for a few days longer. Also if they are inoculated, they will not infect the elders at their place. By extension the elders are also safe.

 

Group 1A, 1B and 1C is very thoroghly crafetd policy by CDC. They look at all the logistics and come up with that stuff. 

 

e.g. during COVVID lockdown in parts of world they closed all the restaurants etc. but kept liquor stores open. Because they understand dependence and scientifically craft policy.

Posted (edited)
56 minutes ago, Jimmy Cliff said:

 

 

 

 

Kary Mullis also thought that HIV did not cause AIDS.  That did not work out too well for him.  So, as brilliant as he was, his opinion is not the be-all end-all. 

 

As for this particular video, it was not made about CoViD 19.  He died in Aug 2019, before the pandemic hit.  

 

But let's take the video at face value.  What he is saying is that, with RT-PCR testing, we can detect very minute amounts of RNA because it is a very powerful technique.  That is correct.  I've used it routinely for my research (for my PhD thesis, I was able to detect very small amounts of RNA using RT-PCR).  But you cannot detect "nothing." There has to be at least a small amount to start with.  In other words, the person has at least some SARS-CoV2 in their nasal cavity. 

 

One unknown is this:  is there enough SARS CoV2 to make the person sick?  This is an unknown because everyone is different and responds differentially to the same viral loads.  So, a tiny amount of SARS CoV2 could make me sick, but not you.  Not only that, a tiny amount may be because the person just recently got infected, and early detection will prompt them to stay away from public and minimize spreading it.  Wouldn't you?   

 

The biggest concern with Covid 19 is asymptomatic spread.  Few other infections have had that issue.  Hence, early detection of tiny quantities of virus, prior to full-blown replication, high viral load and eventual sickness, is a good thing.      

 

As far as lockdowns go, I have always been torn.  The short-term effects on the economy are devastating.  And it hurts a lot of people.  But in a nation where people refuse to wear masks because their idiot (ex) President thought it was uncool, how do you keep them from spreading their snot to others?   Tough choices.  No 100% answers.  All these decisions are of the 51-49 type.

 

 

 

Edited by BacktoCricaddict
Posted

Remember those "CoViD 19 is less dangerous than the flu" memes?  Yeah, that was a long time ago.  Misinformation comes flying out of the blocks.  Needs no evidence or statistical analyses.  No burden of proof.  Just conjecture.  A couple of maverick docs turning hypotheses into conclusions on twitter.  Then the internet takes over.  Memes and videos and yelling journos whipping up hysteria that all docs are cheats, experts are fools, PhDs are worthless, CoViD is a hoax, masks are stupid, and America is great.    

 

Then, the real data follow, limping slowly towards the finish line.  

--------------------------------------------------------------------------------------------------------------------------------

https://www.cmaj.ca/content/early/2021/02/10/cmaj.202795

3.5 x higher risk of mortality.  

 

We described all adults with COVID-19 or influenza discharged from inpatient medical services and medical–surgical intensive care units (ICUs) between Nov. 1, 2019, and June 30, 2020, at 7 hospitals in Toronto and Mississauga, Ontario. We compared patient outcomes using multivariable regression models, controlling for patient sociodemographic factors and comorbidity level. We validated the accuracy of 7 externally developed risk scores to predict mortality among patients with COVID-19.

Results: There were 1027 hospital admissions with COVID-19 (median age 65 yr, 59.1% male) and 783 with influenza (median age 68 yr, 50.8% male). Patients younger than 50 years accounted for 21.2% of all admissions for COVID-19 and 24.0% of ICU admissions. Compared with influenza, patients with COVID-19 had significantly greater in-hospital mortality (unadjusted 19.9% v. 6.1%, adjusted relative risk [RR] 3.46, 95% confidence interval [CI] 2.56–4.68), ICU use (unadjusted 26.4% v. 18.0%, adjusted RR 1.50, 95% CI 1.25–1.80) and hospital length of stay (unadjusted median 8.7 d v. 4.8 d, adjusted rate ratio 1.45, 95% CI 1.25–1.69). Thirty-day readmission was not significantly different (unadjusted 9.3% v. 9.6%, adjusted RR 0.98, 95% CI 0.70–1.39). Three points-based risk scores for predicting in-hospital mortality showed good discrimination (area under the receiver operating characteristic curve [AUC] ranging from 0.72 to 0.81) and calibration.

Interpretation: During the first wave of the pandemic, admission to hospital for COVID-19 was associated with significantly greater mortality, ICU use and hospital length of stay than influenza. Simple risk scores can predict in-hospital mortality in patients with COVID-19 with good accuracy.

 

 

 

Posted

As a symbolic gesture, I hope PM Modiji is taking Covaxin - the completely indigenously developed vaccine by Bharat Biotech.  While Covishield is a perfectly good option from a science standpoint, it was developed by Astra-Zeneca/Oxford and is being manufactured by Serum Instt, Pune.  Commendable that India is helping make it for global supply, but there is something much more special about giving people confidence in the vaccine that was made from scratch in India.  

 

 

Posted
1 hour ago, BacktoCricaddict said:

As a symbolic gesture, I hope PM Modiji is taking Covaxin - the completely indigenously developed vaccine by Bharat Biotech.  While Covishield is a perfectly good option from a science standpoint, it was developed by Astra-Zeneca/Oxford and is being manufactured by Serum Instt, Pune.  Commendable that India is helping make it for global supply, but there is something much more special about giving people confidence in the vaccine that was made from scratch in India.  

 

 

I would be concerned. With no phase 3 data I have no idea how it got approved.

Posted
28 minutes ago, Khota said:

I would be concerned. With no phase 3 data I have no idea how it got approved.


I was approved for emergency use, for healthcare workers and essential services without effectiveness data

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