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Surgical Strike 2.0 ? : DRDO - Institute of Nuclear Medicine & Allied Sciences (INMAS) - 2-deoxy-D-glucose (2-DG) drug - ensures faster recovery of hospitalized patients as well as reducing supplemental oxygen dependence


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Posted (edited)

 

Anti-COVID-19 drug gets DCGI nod for emergency use; can help moderate to severe patients

 

The drug selectively accumulates on infected cells, preventing virus growth by stopping viral synthesis and energy production.

 

I know DCGI is handing out emergency drug use approvals like candies these days, but this is great news.

 

 

 

 

 

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Please discuss.

 

 

Edited by Vilander
Posted
13 minutes ago, Khota said:

Where is the proof???

there is phase 2 trials evidence.. apparently on moderate to severe cases done, its publicly available. 

Posted

 

 

Earlier in April 2020, during the first wave of pandemic INMAS-DRDO scientists conducted laboratory experiments with the help of Centre for Cellular and Molecular Biology (CCMB), Hyderabad and found that this molecule works effectively against SARS-CoV-2 virus and inhibits viral growth. Based on these results, DCGI- CDSCO permitted Phase-II clinical trial of 2-DG in COVID-19 patients in May 2020.

Later, the DCGI further permitted the Phase-III clinical trials in November 2020. The Phase-III clinical trial was conducted on 220 patients during Dec 2020 to March 2021 at 27 COVID hospitals situated in states of Delhi, UP, West Bengal, Gujrat, Rajasthan, Maharashtra, Andhra Pradesh, Telangana, Karnataka and Tamil Nadu. The detailed data of phase-III clinical trial was presented to DCGI.

 

https://www.freepressjournal.in/india/drdos-anti-covid-19-drug-gets-dcgi-nod-for-emergency-use-can-help-moderate-to-severe-patients

Posted

We need to see the phase 3 results. Hope they publish it soon. 

 

But please don't market this as a miracle cure. It might aid the recovery process, but nothing is 100 effective against Covid, not even the vaccines. 

Posted

India’s pharma industry will get a big boost if we can get through this phase and keep ourselves relatively protected for third wave. Vaccines plus generics like these. It will be a pharma boom. 

Posted
8 hours ago, mishra said:

I dont care, I just want to mopve away from vaccine to pill based solution on covid. I do not want to be going into lockdown nxt time vaccination happens.

The crucial thing is it apparently reduced dependence on ventilators which is great for recovery. 

Posted
7 hours ago, ravishingravi said:

If this works it will be game changer. 

They need to combine it with other therapeutics apparently in increases instances of quick recovery out of need for oxygen support in appreciably higher cases.. Hope it works.

Posted (edited)
10 hours ago, beetle said:

We need this to work .

 

If I understand, it stops the virus spread from cell to cell. So effectively, reduces growth of virus. Study needed on its impact on covid patients. I recall Boris Johnson saying that UK is looking to manufacture a pill as well. That too by end of this year

Edited by mishra
Posted
1 hour ago, mishra said:

If I understand, it stops the virus spread from cell to cell. So effectively, reduces growth of virus. Study needed on its impact on covid patients. I recall Boris Johnson saying that UK is looking to manufacture a pill as well. That too by end of this year

Pfizer if i am not wrong is working on a therapeutic drug but again IP, production etc.. this is with DRDO the IP and production with Dr Reddy lab's , really want this to work well... 

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